Horia I. Petrache
Assistant Professor

Email Dr. Petrache

Phone: 317-278-6521

Education

Physics Diploma, University of Bucharest, Romania, 1992
Ph.D., Physics, Carnegie Mellon University, 1998

Research

Measurements of molecular structures and forces by physical methods
including X-ray scattering, Nuclear Magnetic Resonance, and osmotic
stress. We are located in room LD059 in the basement of the Science
Building.

Please visit our research page at http://www.iupui.edu/~lab59.

 

Recent Publications

Petrache I, Fijalkowslka I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR and Tuder RM (2006)
Alpha-1 Antitrypsin Inhibits Caspase-3 Activity Preventing Lung Endothelial Cell Apoptosis.
Am. J. Pathol. 169 1155-1166.

Petrache HI, Zemb T, Belloni L, and Parseigian VA (2006)
Salt Screening and Specific Ion Adsorption Determine Neutral-Lipid Membrane Interactions.
Proc. Natl. Acad. Sci. 103, 7982-7987.

Gondre-Lewis MC, Petrache HI, Wassif CA, Harries D, Parsegian A, Porter FD, and Loh YP (2006)
Abnormal Sterols in Cholesterol-Deficiency Diseases Cause Secretory Granule Malformation and Decreased Membrane Curvature.
J. Cell Science, 119, 1876-1885.

Petrache HI, Tristram-Nagle S, Harries D, Kucerka N, Nagle JF, and Parsegian VA (2006)
Swelling of Phospholipids by Monovalent Salt.
J. Lipid Res. 47, 302-309.

Petrache HI, Kimchi I, Harries D, and Parsegian VA (2005)
Measured Depletion of Ions at the Biomembrane Interface.
J. Am. Chem. Soc. 127, 11546-11547.

Nanda H, Sachs JN, Petrache HI, and Woolf TB (2005)
Environmental Effects on Glycophorin A Folding and Structure Examined by Molecular Simulations.
J. Chem. Theor. Comp. 1, 375-388.

Kucerka N, Liu Y, Chu N, Petrache HI, Tristram-Nagle S, and Nagle JF (2005)
Structure of Fully Hydrated Fluid Phase DMPC and DLPC Lipid Bilayers Using X-Ray Scattering from Oriented Multilamellar Arrays and from Unilamellar Vesicles.
Biophys. J. 88, 2626-2637.

Petrache HI, Harries D, and Parsegian VA (2005)
Alteration of Lipid Membrane Rigidity by Cholesterol and its Metabolic Precursors.
Macromol. Symp. 219, 39-50.

Rajammorthi K, Petrache HI, McIntosh TJ, and Brown MF (2005)
Packing and Viscoelasticity of Polyunsaturated w-3 and w -6 Lipid BilayersÊ as seen by 2H NMR and X-Ray Diffraction.
J. Am. Chem. Soc. 127, 1576-1588.

 

 

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