Horia I. Petrache
Assistant Professor

Email Dr. Petrache

Phone: 317-278-6521

Education

Physics Diploma, University of Bucharest, Romania, 1992
Ph.D., Physics, Carnegie Mellon University, 1998

Research

Measurements of molecular structures and forces by physical methods
including X-ray scattering, Nuclear Magnetic Resonance, and osmotic
stress. We are located in room LD059 in the basement of the Science
Building
.

Please visit our research page at http://www.iupui.edu/~lab59.

 

Recent Publications

D. Danino, E. Kesselman, G. Saper, H. I. Petrache, and D. Harries. Osmotically-induced reversible transitions in lipid-DNA mesophases. Biophys. J., in press.

T. K. Rostovtseva, H. I. Petrache, N. Kazemi, E. Hassanzadeh, and S. M. Bezrukov. Interfacial Polar Interactions Affect Gramicidin Channel Kinetics. Biophys. J.94, L23-25, 2008.

H. I. Petrache, D. Harries, and V. A. Parsegian. Measurement of Lipid forces by X-ray Diffraction and Osmotic Stress. In Methods in Membrane Lipids, A. Dopico (ed.), Humana, 2007.

H. I. Petrache and M. F. Brown. X-ray Scattering and Solid-State 2H NMR Probes of Structural Fluctuations in Lipid Membranes. In Methods in Membrane Lipids, A. Dopico (ed.), Humana, 2007.

Petrache I, Fijalkowslka I, Medler TR, Skirball J, Cruz P, Zhen L, Petrache HI, Flotte TR and Tuder RM. Alpha-1 Antitrypsin Inhibits Caspase-3 Activity Preventing Lung Endothelial Cell Apoptosis. Am. J. Pathol. 169 1155-1166, 2006.

Petrache HI, Zemb T, Belloni L, and Parsegian VA (2006). Salt Screening and Specific Ion Adsorption Determine Neutral-Lipid Membrane Interactions.
Proc. Natl. Acad. Sci. 103, 7982-7987.

Gondre-Lewis MC, Petrache HI, Wassif CA, Harries D, Parsegian A, Porter FD, and Loh YP (2006). Abnormal Sterols in Cholesterol-Deficiency Diseases Cause Secretory Granule Malformation and Decreased Membrane Curvature. J. Cell Science, 119, 1876-1885.

Petrache HI, Tristram-Nagle S, Harries D, Kucerka N, Nagle JF, and Parsegian VA (2006). Swelling of Phospholipids by Monovalent Salt. J. Lipid Res. 47, 302-309.

Petrache HI, Kimchi I, Harries D, and Parsegian VA (2005). Measured Depletion of Ions at the Biomembrane Interface. J. Am. Chem. Soc. 127, 11546-11547.

Nanda H, Sachs JN, Petrache HI, and Woolf TB (2005), Environmental Effects on Glycophorin A Folding and Structure Examined by Molecular Simulations. J. Chem. Theor. Comp. 1, 375-388.

Kucerka N, Liu Y, Chu N, Petrache HI, Tristram-Nagle S, and Nagle JF (2005). Structure of Fully Hydrated Fluid Phase DMPC and DLPC Lipid Bilayers Using X-Ray Scattering from Oriented Multilamellar Arrays and from Unilamellar Vesicles. Biophys. J. 88, 2626-2637.

Petrache HI, Harries D, and Parsegian VA (2005). Alteration of Lipid Membrane Rigidity by Cholesterol and its Metabolic Precursors. Macromol. Symp. 219, 39-50.

Rajammorthi K, Petrache HI, McIntosh TJ, and Brown MF (2005). Packing and Viscoelasticity of Polyunsaturated w-3 and w -6 Lipid Bilayers as seen by 2H NMR and X-Ray Diffraction. J. Am. Chem. Soc. 127, 1576-1588.

 

 

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